Medical Weight Loss in Orange County, California

Physician-supervised GLP-1 weight loss programs that have helped over 5,400 patients. Semaglutide from $166/month. Tirzepatide from $233/month. Serving Costa Mesa, Irvine, Newport Beach, and all of Orange County.

What Is Medical Weight Loss?

Medical weight loss is physician-supervised treatment that uses FDA-approved medications, clinical monitoring, and evidence-based protocols to help patients lose weight safely and sustainably. Unlike commercial diet programs or supplements, medical weight loss addresses the biological factors — hormones, metabolism, and brain chemistry — that make weight loss difficult.

At New Hope Weight Loss, medical weight loss means you receive a prescription medication (semaglutide or tirzepatide) that has been proven in large clinical trials to produce significant, sustained weight loss when combined with reduced caloric intake and increased physical activity. Your treatment is overseen by Dr. Anjmun Sharma, M.D., who reviews your medical history, writes your prescription, and monitors your progress throughout the program.

How GLP-1 Medications Work

GLP-1 (glucagon-like peptide-1) receptor agonists are a class of medications that mimic a natural hormone your body releases after eating. This hormone tells your brain you're full, slows how quickly food leaves your stomach, and helps regulate blood sugar.

The result is a fundamental change in your relationship with food. Patients consistently describe the elimination of "food noise" — the constant mental preoccupation with eating, cravings, and willpower that makes weight loss so exhausting. Instead of fighting your body's hunger signals, GLP-1 medications align them with your weight loss goals.

Programs We Offer

Semaglutide — 90-Day Metabolic Reset (from $166/month)

Our most popular program uses semaglutide, the same active ingredient as Wegovy and Ozempic. Clinical trials (STEP program, NEJM 2021) showed average weight loss of 14.9–16.9% of body weight over 68 weeks. The program includes physician oversight by Dr. Sharma, monthly dosage titration, a dedicated health advisor (bilingual advisors available), and ColdPak-shipped medication.

Tirzepatide — Advanced Program (from $233/month)

Our advanced program uses tirzepatide, the active ingredient in Zepbound and Mounjaro. As a dual GLP-1/GIP receptor agonist, it targets two hormonal pathways. Clinical trials (SURMOUNT program, NEJM 2022) showed weight loss of up to 22.5% of body weight. Ideal for patients seeking maximum results or those who haven't achieved their goals on semaglutide alone.

Who Qualifies?

GLP-1 medications are FDA-approved for adults with a BMI of 30 or higher (obesity), or a BMI of 27 or higher with at least one weight-related condition such as type 2 diabetes, high blood pressure, high cholesterol, or obstructive sleep apnea. You must also not have any contra-indicated conditions — our medical intake questionnaire screens for these.

How to Get Started

Step 1: Take the 2-minute qualifying quiz. Answer a few questions about your health goals to see if GLP-1 treatment may be right for you.

Step 2: Complete the medical intake questionnaire. Provide your health history through our secure, HIPAA-compliant form.

Step 3: Physician review and prescription ($119). Dr. Sharma reviews your medical history, evaluates eligibility, and if approved, writes your personalized GLP-1 prescription. Medication cost is billed separately.

Step 4: Start your program. Receive your medication and begin your Metabolic Reset with ongoing physician support, monthly dosage adjustments, and dedicated health advisor check-ins.

Why Choose New Hope Weight Loss?

Lowest prices in Orange County. Semaglutide from $166/month vs. $300–$800/month at most OC clinics. Same physician-supervised care, same FDA-backed medications.

Real physician oversight. Dr. Sharma personally reviews every patient's medical history — not a nurse practitioner, not an algorithm.

Dedicated health advisors. Kayla Spitzer, Rosalia Avila, and Socorro Avila know your name, your goals, and your progress. Bilingual support available in Spanish.

Transparent pricing. $119 doctor review. $166/month semaglutide. $233/month tirzepatide. No enrollment fees, no hidden charges, no contracts. HSA/FSA accepted.

5,400+ patients treated. We're not new to this. Thousands of patients have trusted New Hope Weight Loss with their health.

Areas We Serve

Our clinic is centrally located in Costa Mesa at 1503 South Coast Drive, Suite 322 — within 15 minutes of most Orange County cities. We serve patients from Irvine, Newport Beach, Santa Ana, Huntington Beach, Anaheim, Tustin, Orange, Fountain Valley, Fullerton, Garden Grove, Laguna Beach, and beyond. Full telemedicine consultations are also available for patients throughout California and select states.

Learn More

Explore our resources to understand your options:

Semaglutide vs. Tirzepatide comparison · Cost guide · Side effects guide · Nutrition guide · HSA/FSA guide · BMI Calculator

Wegovy® and Ozempic® are registered trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are registered trademarks of Eli Lilly and Company. New Hope Weight Loss is not affiliated with, endorsed by, or sponsored by Novo Nordisk or Eli Lilly. Compounded medications are not FDA-approved products.